Author

Zuzanna Sandowska-Markiewicz

The Maria Sklodowska-Curie National Research Institute of Oncology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

David L. EarnshawiD· 2 shared Katarzyna Unrug-BielawskaiD· 2 shared Krzysztof KuśiD· 2 shared Aditi ShastriiD· 1 shared Adrianna Moszyńska· 1 shared Aleksandra Anna MurzyniD· 1 shared Aniela Gołas· 1 shared Artur PirógiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

David L. EarnshawORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mature tumoroids recapitulate clinically relevant drug response through extended 3D culture in PDAC

Krzysztof Kuś, David L. Earnshaw, Artur Piróg, Martyna Siewiera, Sachin Kote, Aleksandra Anna Murzyn, Piotr Świerzewski, Natalia Malek-Trzonkowska, Zuzanna Sandowska-Markiewicz, Katarzyna Unrug-Bielawska, Malgorzata Statkiewicz, Paola Dama, Marcin Przemysław Krzykawski

This study shows that mature tumoroids, grown in 3D culture for ≥10 days, better reflect clinical drug responses in PDAC compared to short-term cultures by capturing microenvironmental effects and transporter-mediated resistance.

bioRxiv · Apr 7, 2026 · PreprintCancer Biology

Romaciclib, a CDK8/CDK19 inhibitor, can overcome venetoclax resistance through a combinatorial strategy

Urszula Pakulska, Marta Obacz, Jerzy Woźnicki, Katarzyna Wiklik, Samarpana Chakraborty, Marta Micek, Vakul Mohanty, Diego Coelho, Elżbieta Adamczyk, Aniela Gołas, Adrianna Moszyńska, Hui Zhang, Magdalena Cybulska, Ewelina Kaniuga, Zuzanna Sandowska-Markiewicz, , Milena M. Mazan

This study shows that romaciclib combined with venetoclax overcomes venetoclax resistance in AML through synergistic apoptosis induction and suppression of resistance pathways.

bioRxiv · Jan 15, 2026 · PreprintCancer Biology

3D culture of pancreatic cancer cells in vitro recapitulates an aberrant mitochondrial oxidative phosphorylation genotype observed in vivo

Krzysztof Kuś, J. Mark Treherne, David L. Earnshaw, Renata Krzykawska, Beata Biesaga, Małgorzata Statkiewicz, Katarzyna Unrug-Bielawska, Zuzanna Sandowska-Markiewicz, Michal Mikula, Javier Antonio Alfaro, Marcin Przemyslaw Krzykawski

This study shows that 3D cultures of pancreatic cancer cells better replicate the mitochondrial oxidative phosphorylation genotype seen in vivo compared to 2D cultures.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology