Author

Hossam Hefesha

BioNTech (Germany)ORCID 0000-0003-3457-9949Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam ZuianiiD· 1 shared Alexander MuikiD· 1 shared Alexandra C. WallsiD· 1 shared Alibek GaleeviD· 1 shared Aniello FedericoiD· 1 shared Asaf PoraniD· 1 shared Ayline KübleriD· 1 shared Charles L. DulbergeriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Adam ZuianiORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 24, 2026

Comprehensive Profiling of Monkeypox Virus Antigens Identifies Potent Targets for Next-Generation mRNA Vaccine Development

Alexandra C. Walls, Harman Malhi, Gavin M. Palowitch…·Adam Zuiani

This study identifies potent MPXV antigens for mRNA vaccine development by testing neutralizing antibodies against various surface proteins in mice.

DOI 10.64898/2026.06.23.733206

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 11, 2026

Lung-targeted cytokine-coding RNA-lipoplexes induce T and NK cell-mediated anti-tumor immune response

Ayline Kübler, Sophie-Christin Linkenbach, Fulvia Vascotto…·Uğur Şahin

This study shows that lung-targeted cytokine RNA-lipoplexes enhance anti-tumor immunity by activating T and NK cells and reducing Tregs, with efficacy in murine models and human lung tumor cultures.

DOI 10.64898/2026.05.06.723126

mousebulk RNA-seq

𝕏 PostBluesky