Khuloud Jaqaman

The paper develops Deep-FISIK, a graph neural network, to predict receptor interaction kinetics from single-molecule imaging data without explicit tracking.

This study identifies integrins and tetraspanins as mediators of CD36-actin coupling, showing their role in CD36 organization and signaling in vascular endothelial cells.

The paper reports structures of full-length neuroligin 2 and its complex with neurexin 1β, showing how their interaction tethers membranes and clusters receptors to form synapses.

The paper investigates CD36 interactome to identify multimolecular complexes involved in anti-angiogenic signaling through proximity biotinylation and functional assays.

This study infers VEGFR2 dimerization kinetics on live cell surfaces using single-molecule imaging and mathematical modeling, revealing differences between full-length and truncated variants.

This study identifies Caveolin-1 as a context-dependent regulator of survival signaling in Ewing Sarcoma, revealing a reversible CD99High state with enhanced survival.

The paper introduces an image analysis method to segment filamentous structures and their intersections in microscopy images by resolving multiple orientations.