Laurie A. Boyer

This paper demonstrates that self-amplifying RNA (saRNA) enables durable, integration-free transgene expression in hiPSCs, supporting cell-fate programming and functional reporter analysis.

HiExM enables scalable single-organelle analysis by improving spatial resolution and throughput, allowing detailed profiling of late endosomes and lysosomes.

This study evaluates dispersion metrics for estimating transcriptional variability in single-cell RNA sequencing data and finds the variance-to-mean ratio is scale-invariant and responsive to noise.

This study shows CFDP1 is required for H2A.Z deposition by the SRCAP chromatin remodeling complex and links CFDP1 deficiency to reduced histone modifications and developmental gene upregulation.

This study identifies RBPMS2 as a conserved regulator of alternative splicing that supports myofibril organization and calcium handling in cardiomyocytes across species.

This study investigates how H2A.Z.1 modulates RNA Polymerase II dynamics during transcription initiation and elongation in embryonic stem cells, revealing its role in pausing and re-initiation.