M Sreepadmanabh

This study shows that oxygen and mechanical cues interact to define distinct cellular states in 3D environments through a reciprocal regulatory coupling.

This paper presents a computational framework to study how cellular self-assembly and migration are influenced by adhesion, motility, and mechanical environment, showing optimal motility for cluster formation and two-stage adhesion effects.

This paper introduces a 3D transparent matrix to study plant-fungal interactions, revealing spatially distinct signaling modules during early infection.

This study shows that 3D physical confinement in yeast delays cell cycle progression by restricting bud volume growth, without affecting transcriptional or proteomic responses.

This study investigates how nematodes navigate 3D granular environments by engineering a transparent matrix and observing non-monotonic propulsive speed responses to physical confinement.

This study develops a mathematical model to predict epithelial wound healing outcomes based on geometric and mechanical properties, validated through experiments on MDCK cells.

The paper shows that physical confinement affects bacterial growth differently based on cell shape, with high aspect-ratio bacteria benefiting more.