Author

David A. Born

Beam Therapeutics (United States)ORCID 0000-0003-3507-9022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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2019-2020 · peak 2/yr

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Giuseppe CiaramellaORCID

Mutual co-authors in cluster

3 papers

GenomicsNature CommunicationsPeer-reviewedApr 28, 2020

The paper develops next-generation cytosine base editors with reduced off-target DNA and RNA deamination and improved on-target activity.

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GenomicsNature BiotechnologyPeer-reviewedApr 13, 2020

This paper evolves adenine base editors (ABE8s) to improve editing efficiency and demonstrates their therapeutic application in human cells.

530 citationstop 1%

GeneticsNature CommunicationsPeer-reviewedApr 5, 2019

The paper shows that genetic evidence linking drug targets to organ system phenotypes predicts clinical trial side effects in those systems.

103 citationstop 1%