Author

Chen-Hao Chiu

Washington University in St. LouisORCID 0000-0003-3524-792XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Brian M. EganiD· 2 shared Daniel L. SchneideriD· 2 shared Franziska PohliD· 2 shared Kerry KornfeldiD· 2 shared Matthew C. MosleyiD· 2 shared Andrea ScharfiD· 1 shared Fong‐Fu HsuiD· 1 shared Hideji FujiwaraiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersDevelopmental Biology

Brian M. EganORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 9, 2025

Environmental NaCl affects C. elegans development and aging

Franziska Pohl, Brian M. Egan, Daniel L. Schneider…·Kerry Kornfeld

This study shows that NaCl in standard C. elegans growth medium accelerates aging and reduces lifespan, with toxicity increasing with age and activating stress response pathways.

DOI 10.1101/2025.03.09.641258

C. elegansexperimental assay

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedJan 29, 2024

The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging

Brian M. Egan, Franziska Pohl, Xavier Anderson…·Kerry Kornfeld

The paper shows captopril extends lifespan in worms and mice by inhibiting ACN-1, which regulates dauer formation and interacts with daf genes.

17 citations

C. elegansmouse

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