Developmental BiologyDevelopmentPeer-reviewed
The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging
Brian M. Egan, Franziska Pohl, Xavier Anderson…·Kerry Kornfeld
The paper shows captopril extends lifespan in worms and mice by inhibiting ACN-1, which regulates dauer formation and interacts with daf genes.
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