Akpéli V. Nordor

This paper identifies CMS4-specific antigen targets in colorectal cancer using a large harmonized multi-omic knowledge base and prioritization pipeline, revealing 236 candidates with therapeutic potential.

InMoose provides a Python implementation of differential expression tools with results similar to R-based tools, ensuring reproducibility across languages.

The paper introduces InMoose, an open-source Python environment for bulk transcriptomic analysis, offering tools for data simulation, batch correction, and differential analysis.

pyComBat provides a Python implementation of ComBat and ComBat-Seq for batch effect correction in microarray and RNA-Seq data, offering similar performance with improved speed and open-source accessibility.

The paper compares transcriptional responses to CRISPR/Cas9-AAV6 genome editing with small molecule perturbations, finding distinct gene expression patterns associated with different editing methods.

The paper identifies hypomethylation patterns in early placenta similar to solid tumors, linking them to genes involved in EMT, immune response, and inflammation.