Author

Sophie Richon

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Virginie Dangles‐MarieiD· 2 shared Akpéli V. NordoriD· 1 shared Arianna FumagalliiD· 1 shared Astrid LièvreiD· 1 shared Briaux Adrien· 1 shared Carlos Perez GonzaleziD· 1 shared Cindy NeuzilletiD· 1 shared Danijela Matic VignjeviciD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Virginie Dangles‐MarieORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Self-organization of tumor heterogeneity and plasticity

Carlos Perez Gonzalez, David B. Brückner, Mickaël Di‐Luoffo, Sophie Richon, Ruchi Goswami, Meryem B. Baghdadi, Florence Piastra-Facon, Neta Felsenthal, Réda Bouras, Arianna Fumagalli, Mirjam C. van der Net, Martijn Gloerich, Salvatore Girardo, Jochen R. Guck, Jacco van Rheenen, , Danijela Matic Vignjevic

This study shows cancer cells follow intrinsic self-organized programs that coordinate tumor cell state transitions during growth, revealing mechanical gradients and stereotyped patterns of heterogeneity and plasticity.

bioRxiv · Oct 9, 2025 · PreprintCancer Biology

IKZF2-ERBB4 gene fusion leads to ERBB4 overexpression in Anal Squamous Cell Carcinoma but with no benefit for ERBB4 inhibition

Sophie Richon, Schnitzler Anne, Lamontagne Julien, Briaux Adrien, Sophie Vacher, Rania El Botty, El Alam Elsy, Pascale Mariani, Cindy Neuzillet, Astrid Lièvre, Wulfran Cacheux, Ivan Bièche, Virginie Dangles‐Marie

The paper identifies an IKZF2-ERBB4 gene fusion in Anal Squamous Cell Carcinoma leading to ERBB4 overexpression but shows that ERBB4 inhibition does not inhibit tumor growth.

bioRxiv · Nov 28, 2024 · PreprintCancer Biology

The early pregnancy human placenta shares hypomethylation patterns characteristic of solid tumors

Akpéli V. Nordor, Djamel Nehar-Belaid, Sophie Richon, David Klatzmann, Dominique H. Bellet, Virginie Dangles‐Marie, Thierry Fournier, Martin J. Aryee

The paper identifies hypomethylation patterns in early placenta similar to solid tumors, linking them to genes involved in EMT, immune response, and inflammation.

Epigenetics · Jul 5, 2017Peer-reviewedGenomics