Da Kuang

The paper evaluates computational predictors for rare variant burden tests and identifies two top predictors that enhance gene-trait association discovery in the UK Biobank.

MaveRegistry is a platform for tracking and sharing multiplexed variant effect assays to reduce redundancy and enable collaboration in variant interpretation.

Proximity-dependent biotinylation (BioID) of 28 SARS-CoV-2 proteins in human cells maps 5,415 proximal interactions with 2,128 host targets across basal and poly(I:C) conditions.

The paper introduces a web-based browser for visualizing 3D genome organization and chromatin interactions, enabling integration with other omics data to study gene regulation.