Author

Ashyad Rayhan

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:database / resource· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Frederick P. RothiD· 4 shared Atina G. CotéiD· 3 shared Dae‐Kyum KimiD· 3 shared DAVID EDWIN HILLiD· 3 shared Dayag SheykhkarimliiD· 3 shared Jennifer J. KnappiD· 3 shared Marc VidaliD· 3 shared Michael A. CalderwoodiD· 3 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersSystems Biology

Frederick P. RothORCID

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Author profile →

4 papers

Recent·Most cited

Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries

Jochen Weile, Gabrielle Ferra, Gabriel E. Boyle, Sriram Pendyala, Clara J. Amorosi, Chiann-Ling C Yeh, Atina G. Coté, Nishka Kishore, Daniel R. Tabet, Warren van Loggerenberg, Ashyad Rayhan, Douglas M. Fowler, Maitreya J. Dunham, Frederick P. Roth

Pacybara improves the accuracy of long-read sequencing for barcoded mutagenized libraries by addressing sequencing errors and non-unique barcodes.

Bioinformatics · Mar 29, 2024Peer-reviewedBioinformatics

A map of binary SARS-CoV-2 protein interactions implicates host immune regulation and ubiquitination

Dae‐Kyum Kim, Benjamin Weller, Chung‐Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, , Pascal Falter‐Braun

The paper maps binary SARS-CoV-2 protein interactions with host proteins, identifying key processes like immune signaling and ubiquitination, and suggests therapeutic targets.

Nature Biotechnology · Oct 10, 2022Peer-reviewedSystems Biology

Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19-associated mechanisms

Estelle M. N. Laurent, Yorgos Sofianatos, Anastassia V. Komarova, Jean‐Pascal Gimeno, Payman Samavarchi‐Tehrani, Dae‐Kyum Kim, Hala S. Abdouni, Marie Duhamel, Patricia Cassonnet, Jennifer J. Knapp, Da Kuang, Aditya Chawla, Dayag Sheykhkarimli, Ashyad Rayhan, Roujia Li, , Étienne Coyaud

Proximity-dependent biotinylation (BioID) of 28 SARS-CoV-2 proteins in human cells maps 5,415 proximal interactions with 2,128 host targets across basal and poly(I:C) conditions.

bioRxiv · Aug 28, 2020 · PreprintSystems Biology

A reference map of the human protein interactome

Katja Luck, Dae‐Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana M. Cafarelli, Francisco Jose Campos-Laborie, Benoît Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven J. Deimling, Alice Desbuleux, , Michael A. Calderwood

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.

bioRxiv · Apr 19, 2019 · PreprintSystems Biology