Cancer BiologybioRxivPreprint
TWIST1 mediated transcriptional activation of SPON2 drives colorectal peritoneal metastasis through activation of cancer-associated fibroblast signaling network
Zhuan Zhou, Alessandro La Ferlita, Manoj H. Palavalli…·Alex C. Kim
This study identifies the SPP1-TWIST1-SPON2 signaling axis as a driver of colorectal peritoneal metastasis through cancer-associated fibroblast signaling.
DOI 10.1101/2025.04.11.648429