Author

Stefan Koch

Linköping UniversityORCID 0000-0003-3579-4229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Claudio CantùiD· 3 shared Lavanya MoparthiiD· 2 shared Simon SöderholmiD· 2 shared Tamina WeissiD· 2 shared Yorick Bernardus Cornelis van de GriftiD· 2 shared Alessandro Mattia· 1 shared Amaia Jauregi‐MigueliD· 1 shared Andreas E. MooriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Claudio CantùORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintApr 24, 2026

GATA transcription factors act as gatekeepers between the Wnt/β-catenin-mediated proliferation and differentiation in the intestinal epithelium

Yorick Bernardus Cornelis van de Grift, Tamina Weiss, Guiliano Castellano…·Claudio Cantù

The paper shows GATA transcription factors modulate Wnt/β-catenin signaling to control cell identity in the intestinal epithelium by repressing secretory lineage genes in stem cells.

DOI 10.64898/2026.04.22.719835

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintDec 18, 2023

The Developmental Transcription Factor TBX3 Physically Engages with the Wnt/β-catenin Transcriptional Complex in Human Colorectal Cancer Cells to Regulate Metastasis Genes

Amaia Jauregi‐Miguel, Simon Söderholm, Tamina Weiss…·Claudio Cantù

This study identifies TBX3 as a functional component of the Wnt/β-catenin complex in human colorectal cancer, showing it modulates metastasis-related transcription through direct protein interactions.

3 citations

humanproteomics

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Molecular BiologybioRxivPreprintJan 17, 2022

The oncogene FOXQ1 is a selective activator of Wnt/β-catenin signalling

Giulia Pizzolato, Lavanya Moparthi, Simon Söderholm…·Stefan Koch

This study identifies FOXQ1 as a bimodal activator of Wnt/β-catenin signalling, functioning through TCF/LEF factors and independent mechanisms.

DOI 10.1101/2022.01.17.476620

humanexperimental assay

𝕏 PostBluesky