Author

Stepan Jerabek

Columbia UniversityORCID 0000-0003-3623-862XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Diego MariniD· 1 shared Dieter M. EgliiD· 1 shared Jia L. XuiD· 1 shared Jishnu Talukdar· 1 shared Julie Sung· 1 shared Nathan R. TreffiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperDevelopmental Biology

Diego MarinORCID

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1 paper

Recent·Most cited

Developmental BiologybioRxivPreprintMay 7, 2025

DSB repair kinetics impair CRISPR-Cas9 editing in human embryos

Dieter M. Egli, Diego Marin, Nathan R. Treff…·Jishnu Talukdar

This study shows that CRISPR-Cas9 editing in human embryos is limited by slow DSB repair kinetics, leading to mosaicism and chromosomal abnormalities.

2 citations

humanCRISPR screen

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