Moshe Elkabets

This study develops a bispecific antibody that enhances T-cell engagement with AXL+ cells, improving anti-PD-1 therapy efficacy in HNSCC by remodeling the tumor microenvironment.

This study identifies HSPD1 as a chaperone for MTHFD2, independent of HSPE1, and shows distinct functional roles for HSPD1 and HSPE1 in mitochondrial biology.

This study shows HSPD1 enhances MYCN expression and tumorigenesis in neuroblastoma by supporting mitochondrial translation and proteostasis.

The paper creates a unified single-cell atlas of HNSCC by integrating scRNA-seq data from 78 patients, revealing HPV and sex-specific differences in the tumor microenvironment.