Author

Shai Kaluski-Kopatch

Ben-Gurion University of the NegevORCID 0000-0002-3457-2299Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Barak RotblatiD· 2 shared Hila Ben-DavidiD· 2 shared Linor CoheniD· 2 shared Moshe ElkabetsiD· 2 shared Shatha S. AlassamiD· 2 shared Shiran DroriD· 2 shared Albert BatushanskyiD· 1 shared Alberto DelaidelliiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

Barak RotblatORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The mitochondrial chaperone HSPD1 folds MTHFD2 independently of its co-chaperone HSPE1

Shani Gabbay, Hila Ben-David, Shatha S. Alassam, Linor Cohen, Tal Levy, Liron Levin, Nili Tickotsky, Ifat Abramovich, Albert Batushansky, Shiran Dror, Moshe Elkabets, Noga Alon, Yariv Brotman, Shai Kaluski-Kopatch, Evelina I. Nikelshparg, , Barak Rotblat

This study identifies HSPD1 as a chaperone for MTHFD2, independent of HSPE1, and shows distinct functional roles for HSPD1 and HSPE1 in mitochondrial biology.

Philosophical Transactions of the Royal Society B Biological Sciences · Oct 1, 2026Peer-reviewedCell Biology

HSPD1 promotes neuroblastoma by augmenting MYCN expression

Shatha S. Alassam, Dinesh Babu Manikandan, Hila Ben-David, Linor Cohen, Shai Kaluski-Kopatch, Laura A. Hruby, Shiran Dror, Poul H. B. Sorensen, Alberto Delaidelli, Gabriel Leprivier, Moshe Elkabets, Barak Rotblat

This study shows HSPD1 enhances MYCN expression and tumorigenesis in neuroblastoma by supporting mitochondrial translation and proteostasis.

bioRxiv · Sep 6, 2026 · PreprintCancer Biology

The Divergent 3D Genome Landscapes of Aging and Neurodegenerative mouse models

Ekaterina Kashuk, Dmitrii Smirnov, Ekaterina Eremenko, Alexandra A. Tsitrina, Dmitrii V. Kriukov, Anastasia Golova, Shai Kaluski-Kopatch, Ekaterina E. Khrameeva, Debra Toiber

This study compares 3D genome changes in aging and neurodegenerative mouse models using Hi-C, finding shared early features and distinct later changes linked to DNA damage.

bioRxiv · Nov 10, 2025 · PreprintMolecular Biology