Author
University of FloridaORCID 0000-0003-3635-8138Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Robin R. Kobylski, Charles K. Min, Jerome C. Nwachukwu…·K.W. Nettles
The paper develops selective glucocorticoid receptor modulators (SGRMs) that modulate immune checkpoint function by altering GR activity states through structural design and machine learning.
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar…·Arun P. Wiita
Structure-optimized CD27-based CAR-T cells targeting CD70 show >80-fold improved expansion in vivo and offer a potential therapy for high-risk multiple myeloma patients.
Daphné Dupéré-Richer, Alberto Riva, Sayantan Maji…·Jonathan D. Licht
This study shows KDM6A regulates immune response genes in multiple myeloma by activating NLRC5 and CIITA, and its loss reduces MHC expression, which can be reversed by HDAC3 inhibitors.