Martin Welch

This study shows that loss of lasR function in Pseudomonas aeruginosa disrupts inter-species interactions in polymicrobial CF airway infections, leading to instability in Candida albicans titres and transcriptional reprogramming.

This study shows that hyphal growth in microfluidic alveoli-like geometries enables coexistence of P. aeruginosa, S. aureus, and C. albicans by creating spatial organization that excludes competitors.

This paper introduces SanntiS, a machine learning tool for identifying biosynthetic gene clusters in genomic and metagenomic data, and demonstrates its ability to predict a large number of novel BGCs with experimental validation.

The paper shows that cooperative activation of dimeric transcription factors can arise from independent ligand binding events and is stabilized by DNA binding.

This study investigates the regulation of carbon flux through the glyoxylate shunt in Pseudomonas aeruginosa by analyzing the structure, kinetics, and reciprocal regulation of its branchpoint enzymes.