Jörn Starruß

This study identifies that a synthetic immune niche enhances T cell cytotoxicity by accelerating lytic hit delivery, not by increasing target encounters or conjugate stability.

FitMultiCell provides a scalable pipeline for modeling, simulating, and parameterizing multi-scale multi-cellular processes using Morpheus and pyABC.

The paper investigates how collective cell migration is robust to different integration strategies of guidance stimuli using an individual-based model.

The paper develops an extended computational model to infer cell motility dynamics from incomplete tracking data in 3D collagen environments, showing it can reliably parameterize motility despite track loss.

The paper shows that polster cells in zebrafish gastrulation are guided by their follower cells through mechanotransduction, enabling long-range coordination of migration.