Author

Manish Kumar Gupta

Center for Interdisciplinary Digital SciencesORCID 0009-0003-9649-1894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Benjamin GeigeriD· 1 shared Haralampos HatzikirouiD· 1 shared Jörn StarrußiD· 1 shared Rawan Zoabi· 1 shared Sofi YadoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Benjamin GeigerORCID

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1 paper

Recent·Most cited

ImmunologyBMC CancerPeer-reviewedOct 15, 2026

Decoupling T Cell Cytotoxicity: A CCL21+ICAM1-Based Synthetic Immune Niche Enhances Tumor Elimination by Accelerating Lytic Hit Delivery

Manish Kumar Gupta, Rawan Zoabi, Sofi Yado…·Haralampos Hatzikirou

This study identifies that a synthetic immune niche enhances T cell cytotoxicity by accelerating lytic hit delivery, not by increasing target encounters or conjugate stability.

DOI 10.1186/s12885-026-16748-y

mouseimaging

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