Qinan Hu

The paper constructs a 3D spatiotemporal multi-omics atlas of Drosophila development, revealing gene regulatory networks and cell type dynamics across embryogenesis to metamorphosis.

CAbiNet jointly visualizes cells and genes using a gene-cell graph and biMAP embedding for interactive exploration and biclustering.

Spateo provides a framework for spatiotemporal modeling of single-cell spatial transcriptomics data to study cell-cell interactions and organ development in 3D space.

This study uses Stereo-seq to generate high-resolution spatiotemporal transcriptomic maps of Drosophila embryos and larvae, revealing new subregions and gene regulatory networks.

The paper improves CRISPR/Cas9 tools for tissue-specific mutagenesis in Drosophila by enhancing gRNA efficiency, enabling cell labeling, and providing genetic reagents for flexible Cas9 deployment.

The paper identifies Trpm as the critical ion channel mediating calcium influx during Drosophila egg activation, showing its conservation with mouse Trpm in calcium signaling.