Gabriel T. Koreman

This study identifies BAF complex interaction with FOS in regulating ASD-associated gene programs through enhancer activation and shows how genetic variants disrupt this process.

The paper identifies human-specific activity-dependent genes regulated by FOS-bound enhancers, showing their role in human brain development evolution.

The paper uses human-chimpanzee tetraploid cells to identify cis-acting gene regulatory changes contributing to human neural specializations.

The paper investigates how Drosophila males adapt their sensory circuits to recognize and respond to pheromones, revealing a modular circuit architecture that enables the evolution of courtship strategies.

The paper improves CRISPR/Cas9 tools for tissue-specific mutagenesis in Drosophila by enhancing gRNA efficiency, enabling cell labeling, and providing genetic reagents for flexible Cas9 deployment.

The paper introduces MAGIC, a CRISPR/Cas9-based method to generate mosaic animals in Drosophila by inducing DNA double-strand breaks, enabling efficient gene function studies and fluorescent clone generation.