Author

Sina Kanannejad

Human TechnopoleORCID 0009-0002-1647-2873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Alice GiustacchiniiD· 3 shared Macarena Oporto EspuelasiD· 2 shared Soumick ChatterjeeiD· 2 shared Alessandro CuomoiD· 1 shared Amir FardiniD· 1 shared Andrea Francesco BenvenutoiD· 1 shared Andrea RaimondiiD· 1 shared Aurora Casiraghi· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

Alice GiustacchiniORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Recurrent leukaemia stem cell states define the antigenic landscape of paediatric Acute Myeloid Leukaemia

Sina Kanannejad, Macarena Oporto Espuelas, Claudia D’Oria, Filippo Martignano, Ilaria Marina Michelozzi, Soumick Chatterjee, Edoardo Giacopuzzi, Eduardo Gomez Castaneda, Aurora Casiraghi, Theodoros Xenakis, George T. Hall, Efstratios Kirtsios, Cecilia Reyneri, Hannah L. Macpherson, Jack Luke Bartram, , Alice Giustacchini

This study identifies three leukaemia stem cell subtypes in paediatric AML and shows that combining CLEC12A and CD84 targets all subtypes while sparing healthy cells.

bioRxiv · Oct 23, 2026 · PreprintCancer Biology

scINTILLA: Single-Cell Integrated Inference, Labelling, and Landscape Analysis for Cell-Type Annotation Quality Assessment

Sina Kanannejad, Noemi Bongiorni, Elisa Nordera, Sara Redaelli, Irene Rusconi, Rachele Zanin, Alice Giustacchini, Soumick Chatterjee

scINTILLA assesses cell-type annotation quality in single-cell datasets by combining supervised and unsupervised learning to identify label ambiguity and hidden heterogeneity.

bioRxiv · Jul 28, 2026 · PreprintBioinformatics

Targeting GL-Lect driven endocytosis to suppress cell plasticity in breast cancer

Amir Fardin, Andrea Francesco Benvenuto, Irene Schiano Lomoriello, Chiara Tordonato, Micaela Quarto, Stefano Freddi, Giovanni Giangreco, Giovanni Bertalot, Francesca Montani, Ivan Nicola Colaluca, Roberta Cacciatore, Andrea Raimondi, Maria Giovanna Jodice, Maria Grazia Malabarba, Luigi Scietti, , Sara Sigismund

This study identifies GL-Lect driven endocytosis as a driver of metastatic plasticity in breast cancer and shows pharmacologic inhibition can suppress invasive phenotypes.

bioRxiv · Jan 8, 2026 · PreprintCancer Biology

Integrated in silico and in vitro approaches identify a HSP90 drug vulnerability axis in t(7;12) infant leukemia stem-like cells

Ylenia Cicirò, Denise Ragusa, Emily M. Johnson, Ayona Johns, Sina Kanannejad, Remisha Gurung, Macarena Oporto Espuelas, Chun-Wai Wade Suen, Gabriel Torregrosa-Cortés, Alice Giustacchini, Sabrina Tosi, Cristina Pina

The paper identifies HSP90 inhibitors as potential therapies for t(7;12)-AML by combining computational drug screening with in vitro experiments.

bioRxiv · Sep 6, 2025 · PreprintCancer Biology