Author

S H Jones

British Heart FoundationORCID 0009-0003-3572-1502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander J. SparrowiD· 1 shared Andrew R. JonesiD· 1 shared Anne McArdleiD· 1 shared Betty RamaniD· 1 shared Charlotte L. Hooper· 1 shared Christopher McArdle· 1 shared Christopher N. ToepferiD· 1 shared Claire E. EyersiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alexander J. SparrowORCID

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2 papers

Recent·Most cited

Unmasking Supervillin: SVIL haploinsufficiency causes hypertrophic cardiomyopathy by impairing mechanotransduction and cellular energetics.

Yifan Joshua Li, Yiangos Psaras, Violetta Steeples, Josephine M Watkins, Charlotte L. Hooper, Marta Moya‐Jódar, T. NICOL, Alexander J. Sparrow, Marcos Garcia-Lacarte, S H Jones, Isabelle Bond, Niklas Beyhoff, Paul Robinson, Marieluise Kirchner, Philipp Mertins, , Christopher N. Toepfer

This study identifies SVIL haploinsufficiency as a cause of hypertrophic cardiomyopathy by impairing mechanotransduction and cellular energetics, with potential therapeutic implications for mitochondrial-targeted treatments.

bioRxiv · Jul 24, 2026 · PreprintCell Biology

MicroAge Mission: Effects of Microgravity and Heat Shock Protein 10 Overexpression on the Proteome of Human Tissue-Engineered Muscle Constructs - Implications for Skeletal Muscle Ageing

S H Jones, Megan Hasoon, Kareena Adair, Shahjahan M. Shigdar, Kay Hemmings, James R. Henstock, Philip Brownridge, Christopher McArdle, Gianluca Neri, William Blackler, Georgi Olentsenko, Andrew R. Jones, Claire E. Eyers, Kai F. Hoettges, Malcolm Joseph Jackson, Anne McArdle

This study examines proteomic changes in human muscle constructs under microgravity and shows that HSP10 overexpression reduces these changes, suggesting a potential strategy for combating muscle atrophy.

bioRxiv · Apr 30, 2026 · PreprintPhysiology