Anne McArdle

MicroAge Mission: Effects of Microgravity and Heat Shock Protein 10 Overexpression on the Proteome of Human Tissue-Engineered Muscle Constructs - Implications for Skeletal Muscle Ageing

This study examines proteomic changes in human muscle constructs under microgravity and shows that HSP10 overexpression reduces these changes, suggesting a potential strategy for combating muscle atrophy.

MicroAge Mission: Experimental Design, Hardware Development and Operational Considerations for a Bespoke Culture System to Support Tissue-Engineered Skeletal Muscle Constructs.

The paper describes the design and operational considerations of a tissue-engineered skeletal muscle system for microgravity experiments to study muscle atrophy and aging mechanisms.

Peroxiredoxin 2 mediates redox-stimulated adaptations to oxidative phosphorylation induced by contractile activity in human skeletal muscle myotubes

This study shows that PRDX2 mediates redox-stimulated adaptations to oxidative phosphorylation in human skeletal muscle myotubes exposed to contractile activity or H2O2.

Age-related changes in microRNAs expression in cruciate ligaments of wild-stock house mice

This study identifies age-related upregulation of miR-29a and miR-34a in murine cruciate ligaments and their association with collagen expression and inflammation pathways.