Author

John H. Adams

University of South FloridaORCID 0000-0003-3707-7979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jenna OberstalleriD· 3 shared Chengqi C. Q. WangiD· 2 shared Min ZhangiD· 2 shared Rays H. Y. JiangiD· 2 shared Thomas D. OttoiD· 2 shared Camilla Valente PiresiD· 1 shared Chang LiiD· 1 shared Daniel E. GoldbergiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

Jenna OberstallerORCID

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3 papers

Recent·Most cited

BiochemistryScience AdvancesPeer-reviewedDec 18, 2024

The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis

Zhemin Zhang, Meinan Lyu, Han Xu…·Edward W. Yu

This paper presents three structures of PfNCR1, a Plasmodium falciparum membrane protein, and shows it exports cholesterol to maintain membrane homeostasis, with MMV009108 inhibiting this function.

9 citations

plant (other)cryo-EM

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BioinformaticsGenome biologyPeer-reviewedOct 16, 2023

MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites

Chengqi C. Q. Wang, Yibo Dong, Chang Li…·Xiaoming Liu

MalariaSED predicts chromatin profiles in malaria parasites and identifies noncoding variants linked to invasion and drug resistance.

6 citations

ChIP-seqdeep learning

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GenomicsNature CommunicationsPeer-reviewedJul 27, 2021

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite

Min Zhang, Chengqi C. Q. Wang, Jenna Oberstaller…·John H. Adams

The paper identifies genes in Plasmodium falciparum that enable survival at febrile temperatures and links these to artemisinin resistance through apicoplast-related pathways.

62 citationstop 1%

humanexperimental assay

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