Renee J. Seto

The paper identifies glial cells as the gatekeepers for small RNA transport from the germline to the nervous system in C. elegans, revealing a mechanism for transgenerational epigenetic inheritance of behavior.

This paper identifies molecular mechanisms underlying transgenerational epigenetic inheritance of pathogen avoidance in C. elegans, showing that specific small RNAs from bacteria mediate this behavior across generations.

The paper critiques Gainey et al.'s failure to replicate transgenerational epigenetic inheritance experiments in C. elegans due to methodological deviations.

The paper shows that PF15 small RNA Pfs1 induces transgenerational avoidance of PF15 in C. elegans by targeting the vab-1 Ephrin receptor gene, revealing a new bacterial sRNA/C. elegans gene target pair involved in pathogen avoidance.

The paper shows a bacterial small RNA induces transgenerational learned avoidance in C. elegans, with potential maladaptive effects on beneficial bacteria.