Jonathan St. Ange

The paper profiles single-nucleus RNA sequencing data from male and hermaphrodite C. elegans neurons to identify sex-specific and sex-shared transcriptional regulators of behavior.

Single-nucleus RNA sequencing of adult C. elegans neurons identifies transcriptional changes in daf-2 mutants related to chemosensation, learning, and memory.

The paper shows a bacterial small RNA induces transgenerational learned avoidance in C. elegans, with potential maladaptive effects on beneficial bacteria.

Activating the Gαq pathway in aged worms and mice improves memory and cognitive function, demonstrating conservation across species.