Author

Luis Edgardo Gonzales-Huerta

Universidad San Ignacio de LoyolaORCID 0000-0003-3736-6850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Darius P. H. Armstrong-JamesiD· 3 shared Thomas J WilliamsiD· 3 shared Brian D. RobertsoniD· 2 shared Carlton A. EvansiD· 2 shared Renad AljohaniiD· 2 shared A. Reed· 1 shared Anand ShahiD· 1 shared David Bell· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

Darius P. H. Armstrong-JamesORCID

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3 papers

Recent·Most cited

ImmunologyPLoS ONEPeer-reviewedJul 9, 2026

Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro

Luis Edgardo Gonzales-Huerta, Thomas J Williams, Renad Aljohani…·Darius P. H. Armstrong-James

This study shows that mycobacterial lipoarabinomannan impairs macrophage ability to kill Aspergillus fumigatus conidia and increases inflammatory cytokine release in vitro.

1 citation

mouseproteomics

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ImmunologyAllergyPeer-reviewedFeb 11, 2026

Selective targeting of IL-1RAP-dependent eosinophilic inflammation in allergic fungal airway disease

Thomas J Williams, James S. Griffiths, Luis Edgardo Gonzales-Huerta…·Darius P. H. Armstrong-James

This study identifies IL-1RAP as a target for reducing eosinophilia in allergic fungal airway disease using a mouse model of chronic A. fumigatus exposure.

1 citation

mousebulk RNA-seq

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ImmunologybioRxivPreprintNov 15, 2024

Precision-cut lung slices in air-liquid interface (PCLS-ALI): A novel ex-vivo model for the study of Pulmonary Aspergillosis

Luis Edgardo Gonzales-Huerta, Thomas J Williams, Renad Aljohani…·Darius P. H. Armstrong-James

The paper introduces a novel ex-vivo model using precision-cut lung slices in air-liquid interface to study Pulmonary Aspergillosis and assess antifungal treatments.

2 citations

mouseexperimental assay

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