Edward A. Dennis

This study shows that saturated cardiolipins (CLsat) disrupt inner mitochondrial membrane structure and function, contributing to mitochondrial dysfunction in Barth syndrome.

This study shows eukaryotic cells maintain lipid curvature homeostasis under pressure through metabolic adjustments, with yeast and human cells using different mechanisms.

This study uses molecular dynamics simulations to show that membrane association of cPLA2 triggers conformational changes that enable its activation and phospholipid hydrolysis.