Adrian M. Wong

This study shows that saturated cardiolipins (CLsat) disrupt inner mitochondrial membrane structure and function, contributing to mitochondrial dysfunction in Barth syndrome.

The paper identifies Npc2's role in sphingolipid transport to the yeast vacuole, showing it supports membrane phase separation during micro-lipophagy.

This study investigates how 1-deoxysphingolipids affect membrane properties and cargo trafficking in the early secretory pathway by analyzing their subcellular distribution and effects on ER membrane fluidity and ERES.

The paper identifies LPCAT3 as a cold-regulated enzyme that generates AA-PE in BAT mitochondria, enhancing ETC efficiency and thermogenesis.

This study develops organelle-targeted Laurdan probes to measure membrane packing heterogeneity and responses to saturated lipid stress in specific cellular compartments.