Systems BiologybioRxivPreprint
Machine Learning and Optimal Control of Enzyme Activities to Preserve Solvent Capacity in the Cell
Samuel R. Britton, Mark Alber, William R. Cannon
The paper predicts enzyme regulation policies using statistical thermodynamics and hybrid optimization-reinforcement learning to maintain solvent capacity in E. coli central metabolism.
DOI 10.1101/2020.04.06.028035