Purusharth I Rajyaguru

This study shows PRMT1/Hmt1 reduces α-synuclein aggregates and toxicity without requiring their methyltransferase activity, revealing a new pathway for protein quality control.

This study identifies Scd6's role in regulating oxidative stress response by modulating Ctt1 mRNA levels in yeast.

This paper shows that DDX3X syndrome mutations cause solid-like stress granules and neuronal death by altering DDX3X-RNA conformation.

This study shows that RNP condensates in yeast help survive Mars-like stress conditions, including shock waves and perchlorate, by forming P-bodies and modulating gene expression.

This study identifies Sbp1 as a regulator of autophagy during genotoxic stress by modulating translation of autophagy genes and upstream activators.

This study identifies an RGG peptide that disassembles ALS-associated condensates by reducing toxicity and restoring nuclear localization in FUS mutants.