Author

Nicholas S. Giroux

Duke UniversityORCID 0000-0003-3801-4689Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alejandro BarreraiD· 1 shared Bradly P. NicholsoniD· 1 shared Bryan D. KraftiD· 1 shared Christopher W. WoodsiD· 1 shared Elizabeth PetzoldiD· 1 shared Emily R. KoiD· 1 shared Ephraim L. TsalikiD· 1 shared Ergang WangiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alejandro BarreraORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 16, 2025

The gene regulatory effects of selective glucocorticoid receptor ligands

Nicholas S. Giroux, Graham D. Johnson, Alejandro Barrera, Timothy E. Reddy

The paper evaluates the gene regulatory effects of ten synthetic glucocorticoid receptor ligands using mRNA-seq and STARR-seq, finding their responses correlate with dexamethasone and are not selective to subsets of the molecular GC response.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintDec 4, 2020

Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity

Nicholas S. Giroux, Shengli Ding, Micah T. McClain…·Xiling Shen

Chromatin accessibility in immune cells from COVID-19 subjects is remodeled prior to seroconversion to reflect disease severity.

9 citations

humanATAC-seq

𝕏 PostBluesky