Author
Duke UniversityORCID 0000-0001-8034-1136Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Wenliang Wang, Manoj Hariharan, Wubin Ding…·Joseph R. Ecker
This study identifies how genetic and environmental factors shape the human immune cell epigenome through differential methylation and chromatin accessibility changes.
Matthew W. Foster, T. McMahon, James S. Ngocho…·Matthew P. Rubach
The paper quantifies proteins and post-translational modifications in dried blood from sepsis patients in Tanzania, revealing proteome signatures of inflammation and correlations with clinical markers.
William Thistlethwaite, Sindhu Vangeti, Wan-Sze Cheng…·Stuart C. Sealfon
The paper analyzes the epigenomic changes in innate immune cells after influenza virus infection and finds coordinated rewiring of the epigenetic landscape.
Irem B. Gündüz, Bei Wei, Derek C. Chen…·William James Greenleaf
The paper presents a multimodal epigenome atlas of human immune cells exposed to viral and chemical agents, revealing epigenetic changes in transcription factor binding sites and cytokine networks.
Benjamin H. Schott, Liuyang Wang, Xinyu Zhu…·Dennis C. Ko
The paper identifies a nonsynonymous ERAP1 variant associated with increased susceptibility to influenza virus using scHi-HOST, a single-cell method for genetic susceptibility testing.
Liuyang Wang, Thomas J. Balmat, Alejandro L. Antonia…·Dennis C. Ko
The paper connects genetic architecture of human diseases with molecular phenotypes to uncover mechanisms of COVID-19 susceptibility.