Author

Isabel H. Salas

Salk Institute for Biological StudiesORCID 0000-0003-3874-9319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrien PaumieriD· 2 shared Nicola J. AlleniD· 2 shared Aksinya DerevyankoiD· 1 shared Alexandra P BosworthiD· 1 shared Arash FassihiiD· 1 shared Corey Switzler· 1 shared Jillybeth BurgadoiD· 1 shared Laura SanchoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Adrien PaumierORCID

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2 papers

Recent·Most cited

NeuroscienceCell ReportsPeer-reviewedMar 1, 2025

Astrocyte glypican 5 regulates synapse maturation and stabilization

Alexandra P Bosworth, Minerva Contreras, Laura Sancho…·Nicola J. Allen

This study shows astrocyte glypican 5 is necessary for synapse maturation and stabilization in the developing mouse cortex, with implications for neurological disorders.

30 citationstop 1%

mouseexperimental assay

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NeurosciencebioRxivPreprintOct 30, 2024

Astrocyte transcriptomic analysis identifies glypican 5 downregulation as a contributor to synaptic dysfunction in Alzheimer disease models

Isabel H. Salas, Adrien Paumier, Tao Tao…·Nicola J. Allen

The paper identifies glypican 5 downregulation in astrocytes as a contributor to synaptic dysfunction in Alzheimer's disease models and shows its reversal can improve cognitive function.

6 citations

mousebulk RNA-seq

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