Author

Alexandra P Bosworth

Salk Institute for Biological StudiesORCID 0000-0003-4234-615XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Laura SanchoiD· 2 shared Nicola J. AlleniD· 2 shared Adrien PaumieriD· 1 shared Alison L. M. Caldwell· 1 shared Audrey G. Miglietta· 1 shared Isabel H. SalasiD· 1 shared James DengiD· 1 shared Jolene K. DiedrichiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Laura SanchoORCID

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2 papers

Recent·Most cited

NeuroscienceCell ReportsPeer-reviewedMar 1, 2025

Astrocyte glypican 5 regulates synapse maturation and stabilization

Alexandra P Bosworth, Minerva Contreras, Laura Sancho…·Nicola J. Allen

This study shows astrocyte glypican 5 is necessary for synapse maturation and stabilization in the developing mouse cortex, with implications for neurological disorders.

30 citationstop 1%

mouseexperimental assay

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NeuroscienceNature NeurosciencePeer-reviewedAug 30, 2022

Aberrant astrocyte protein secretion contributes to altered neuronal development in diverse disorders

Alison L. M. Caldwell, Laura Sancho, James Deng…·Nicola J. Allen

The paper identifies disorder-specific and shared changes in astrocyte protein secretion and gene expression in neurodevelopmental disorders, linking increased Igfbp2 and BMP signaling to altered neuronal development.

86 citationstop 1%

humanproteomics

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