Joseph J. Raymond

Temporal Biodynamics identifies stage-relevant targets and biomarkers by modeling disease progression using AI, improving detection of disease-associated genes and proteins over traditional methods.

The paper uses patient brain organoids to show that 16p11.2 CNVs affect RBFOX1 expression and link it to neurodevelopmental disorders.

The paper identifies a common genetic variant in IFITM3 that explains most inter-individual variation in neural progenitor cell susceptibility to Zika virus using natural genetic variation and synthetic perturbations.