Janine L. Brown

The paper investigates whether early-life maternal loss in African savanna elephants leads to accelerated DNA methylation age and distinct epigenetic signatures, finding instead a younger epigenetic age and limited differential methylation.

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

The paper provides genomic resources for Asian and African savannah elephants to aid conservation and health research through genome sequencing, mutation rate estimation, demographic reconstruction, and a capture assay for genotyping.

This paper develops epigenetic clocks for African and Asian elephants using DNA methylation data to estimate age and identify age-related CpGs and their associated genes.