Author

Sinisa Dovat

Pennsylvania State UniversityORCID 0000-0003-3906-6165Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Chandrika Gowda Behura· 2 shared Hannah ValensiiD· 2 shared Jeremy A. HengstiD· 2 shared Katherine Mercer· 2 shared Marudhu Pandiyan ShanmugamiD· 2 shared Rajesh Rajaiah· 2 shared Suming HuangiD· 2 shared Upendarrao GollaiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Chandrika Gowda Behura

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 15, 2026

Lineage-specific CK2α deletion reshapes the transcriptome of hematopoietic stem cells toward an immune-primed state

Hannah Valensi, Rajesh Rajaiah, Marudhu Pandiyan Shanmugam…·Yasin Uzun

This study shows that deleting CK2α in hematopoietic stem cells (HSCs) alters their transcriptome toward an immune-primed state, with tissue-specific effects on inflammatory and immune-related genes.

DOI 10.64898/2026.04.10.717787

mousescRNA-seq

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Pharmacology & ToxicologybioRxivPreprintDec 26, 2025

CK2 inhibitor, CX-4945, enhances BH3 priming and promotes apoptosis of venetoclax-resistant AML by targeting antiapoptotic proteins

Muhammad Daniyal, Rajesh Rajaiah, Upendarrao Golla…·Chandrika Gowda Behura

DOI 10.64898/2025.12.24.696284

humanexperimental assay

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BioinformaticsLeukemiaPeer-reviewedJun 24, 2025

Critical roles of Ikaros and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia

Yali Ding, Bing He, Daniel Bogush…·Sinisa Dovat

This study identifies Ikaros and HDAC1's roles in regulating heterochromatin and tumor suppression in T-ALL by modulating EZH2 activity and chromatin structure.

3 citations

humanmouse

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