Author
Pennsylvania State UniversityORCID 0000-0003-0519-7087Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Hannah Valensi, Rajesh Rajaiah, Marudhu Pandiyan Shanmugam…·Yasin Uzun
This study shows that deleting CK2α in hematopoietic stem cells (HSCs) alters their transcriptome toward an immune-primed state, with tissue-specific effects on inflammatory and immune-related genes.
Muhammad Daniyal, Rajesh Rajaiah, Upendarrao Golla…·Chandrika Gowda Behura
Muhammad Daniyal, Rajesh Rajaiah, Upendarrao Golla…·Chandrika Gowda Behura
This study shows that CK2 inhibitor CX-4945 targets EWS-FLI1 and reduces tumor growth and metastasis in Ewing Sarcoma models.
Johnson Ung, Su‐Fern Tan, Jeremy J.P. Shaw…·Thomas P. Loughran
This study shows that inhibiting acid ceramidase (AC) enhances venetoclax's effectiveness in venetoclax-resistant AML by inducing a cytotoxic integrated stress response.
B. Bishal Paudel, Su‐Fern Tan, Todd E. Fox…·Thomas P. Loughran
This study identifies two sphingolipidomic subtypes in AML, with one subtype associated with poor clinical outcomes and high-risk features.