Author

Alina Sieber

Ludwig-Maximilians-Universität MünchenORCID 0000-0003-3910-6868Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jürgen LassakiD· 2 shared Andreas SchlundtiD· 1 shared Anna Schäpers· 1 shared Dmitrij FrishmaniD· 1 shared Fei QiiD· 1 shared Giovanni GalloiD· 1 shared Julian von EhriD· 1 shared Karthikeyan DhamotharaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSynthetic Biology

Jürgen LassakORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJul 8, 2026

Reprogramming a Protein Ligase for Genetic Code Expansion

Giovanni Gallo, Alina Sieber, Michael Hellwig…·Jürgen Lassak

This paper reprograms a protein ligase into a functional aminoacyl-tRNA synthetase, enabling the incorporation of non-canonical amino acids and post-translational modifications into proteins.

DOI 10.64898/2026.07.07.736966

E. coliproteomics

𝕏 PostBluesky

MicrobiologyNature CommunicationsPeer-reviewedDec 2, 2024

EF-P and its paralog EfpL (YeiP) differentially control translation of proline containing sequences

Alina Sieber, Marina Parr, Julian von Ehr…·Jürgen Lassak

This study identifies EfpL as a ribosome rescue factor that senses cellular metabolic state, complementing EF-P in proline-containing sequence translation.

14 citations

E. coliproteomics

𝕏 PostBluesky