Fei Qi

The paper identifies millions of self-cleaving ribozymes in humans and other species, revealing a much larger ribozyme-ome than previously thought and their potential roles in gene regulation and biotechnology.

The paper shows that the enzyme SpeC in enterobacteria degrades Nε-modified lysine derivatives, producing biogenic amines and enabling microbial utilization of these compounds as nitrogen sources.

This study identifies EfpL as a ribosome rescue factor that senses cellular metabolic state, complementing EF-P in proline-containing sequence translation.