ImmunologybioRxivPreprint
Knockdown of the long isoform of the prolactin receptor selectively targets pathogenic immune cells and averts lupus nephritis
Kory Hamane, Zunsong Hu, João Rodrigues Lima-Júnior…·Srividya Swaminathan
This study shows that knocking down the long isoform of the prolactin receptor reduces pathogenic immune cells and prevents lupus nephritis in SLE-prone mice.