Author

Holly M. Robb

AbbVie (United States)ORCID 0000-0003-3982-4587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Carmela SidrauskiiD· 2 shared Ana Maria Basso· 1 shared Andrea T. Ireland· 1 shared Andrew M. Swensen· 1 shared Arthur L. Nikkel· 1 shared Bryan King· 1 shared Bryson D. BennettiD· 1 shared Caitlin F. ConnellyiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Carmela SidrauskiORCID

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2 papers

Recent·Most cited

NeuroscienceJCI InsightPeer-reviewedJul 15, 2025

eIF2B Activator Rescues Neonatal Lethality of an eIF2Bα Sugar Phosphate Binding Mutation Associated with Vanishing White Matter Disease

Karin Lin, Nina Ly, Rejani B. Kunjamma…·Carmela Sidrauski

This paper shows that an eIF2B activator rescues neonatal lethality in a VWM mouse model but leads to age-related motor deficits and myelin loss.

6 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedJan 9, 2019

eIF2B activator prevents neurological defects caused by a chronic Integrated Stress Response

Yao Liang Wong, Lauren LeBon, Ana Maria Basso…·Carmela Sidrauski

The paper shows that a novel eIF2B activator prevents neurological defects in a mouse model of Vanishing White Matter disease by normalizing the transcriptome and proteome.

234 citationstop 1%

mouseexperimental assay

𝕏 PostBluesky