Author

Rejani B. Kunjamma

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Brian PopkoiD· 3 shared Jonah R. ChaniD· 2 shared Yanan CheniD· 2 shared Bryan King· 1 shared Bryson D. BennettiD· 1 shared Caitlin F. ConnellyiD· 1 shared Carmela SidrauskiiD· 1 shared Chunlian ZhangiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersNeuroscience

Brian PopkoORCID

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4 papers

Recent·Most cited

eIF2B Activator Rescues Neonatal Lethality of an eIF2Bα Sugar Phosphate Binding Mutation Associated with Vanishing White Matter Disease

Karin Lin, Nina Ly, Rejani B. Kunjamma, Ngoc Vu, Bryan King, Holly M. Robb, Eric G. Mohler, Janani Sridar, Qi Hao, Jose Zavala‐Solorio, Chunlian Zhang, Varahram Shahryari, Nick van Bruggen, Caitlin F. Connelly, Bryson D. Bennett, , Carmela Sidrauski

This paper shows that an eIF2B activator rescues neonatal lethality in a VWM mouse model but leads to age-related motor deficits and myelin loss.

JCI Insight · Jul 15, 2025Peer-reviewedNeuroscience

Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response

Yanan Chen, Songhua Quan, Vaibhav Patil, Rejani B. Kunjamma, Haley M. Tokars, Eric D. Leisten, Godwin Joy, Samantha Wills, Jonah R. Chan, Yvette C. Wong, Brian Popko

This study investigates how combining Sephin1 and BZA accelerates remyelination under inflammation by modulating the integrated stress response in oligodendrocytes.

Glia · May 19, 2023Peer-reviewedNeuroscience

Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment

Yanan Chen, Rejani B. Kunjamma, Molly Weiner, Jonah R. Chan, Brian Popko

This study shows that enhancing the integrated stress response (ISR) improves remyelination in inflammatory CNS lesions in mice.

eLife · Mar 22, 2021Peer-reviewedNeuroscience

Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease

Sebastian Werneburg, Jonathan Jung, Rejani B. Kunjamma, Seung-Kwon Ha, Nicholas J. Luciano, Cory M. Willis, Guangping Gao, Natália P. Biscola, Leif A. Havton, Stephen J. Crocker, Brian Popko, Daniel S. Reich, Dorothy P. Schafer

This study identifies synapse loss and microglial synaptic engulfment in MS models and demonstrates that targeted complement inhibition prevents synapse loss and visual dysfunction.

Immunity · Dec 26, 2019Peer-reviewedNeuroscience