Norbert B. Ghyselinck

This study shows that loss of NR5A1 in Sertoli cells after sex determination leads to their transdifferentiation, anoikis, and testis abnormalities.

The paper identifies and characterizes a previously uncharacterized supporting-like cell lineage in developing mouse gonads, showing its origin, specification, and sex-specific differentiation.

This study shows direct RA signaling in cardiomyocytes protects against apoptosis after MI in mice by identifying Tgm2 and Ace1 as RA targets.

The paper investigates the development of extraocular muscles, identifying retinoic acid's role in their formation and tendon attachment sites.

This study shows that retinoic acid receptors are not required for meiosis initiation in mouse fetal ovaries, challenging the current model and suggesting a role for CYP26B1 in meiosis prevention.