PathologybioRxivPreprint
Clonal hematopoiesis driven by Dnmt3a mutations promotes metabolic disease development
Bowen Yan, Qingchen Yuan, Prabhjot Kaur…·Olga A. Guryanova
This study shows that Dnmt3a mutations in clonal hematopoiesis drive metabolic diseases like obesity and diabetes in mice, especially under high-fat diet.
DOI 10.1101/2025.05.02.651715