Author

James O McNamara

Duke UniversityORCID 0000-0003-4091-618XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Arvin Deshmukh· 1 shared Charles A. GersbachiD· 1 shared Derek G. SouthwelliD· 1 shared Diego Arroyo· 1 shared Dmitry VelmesheviD· 1 shared Elizabeth A. MatthewsiD· 1 shared Enhui Pan· 1 shared Jing XuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Arvin Deshmukh

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintNov 3, 2025

Circuit-specific gene editing for precision modulation of neuronal activity with CRISPR-rabies virus

Zijian Zhang, Jing Xu, Elizabeth A. Matthews…·Dmitry Velmeshev

The paper introduces CRISPR-rabies virus (CRV) to enable precise circuit-level gene modulation in neurons, demonstrating its ability to regulate synaptic transmission in the hippocampus.

DOI 10.1101/2025.11.03.686433

mouseCRISPR screen

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